Roy Chowdhury Lab

Human Coronary Plaque T Cells Are Clonal and Cross-React to Virus and Self

Roy Chowdhury R, Jessica D’Addabbo, Xianxi Huang , Stefan Veizades, Koki Sasagawa, David M. Louis , Paul Cheng, Jan Sokol, Annie Jensen, Alexandria Tso , Vishnu Shankar, Ben Shogo Wendel , Isaac Bakerman, Grace Liang, Tiffany Koyano, Robyn Fong, Allison N. Nau , Herra Ahmad , Jayakrishnan Gopakumar , Robert Wirka, Andrew S. Lee, Jack Boyd, Y. Joseph Woo , Thomas Quertermous , Gunsagar Singh Gulati , Siddhartha Jaiswal , Yueh-Hsiu Chien, Charles Kwok Fai Chan, Mark M. Davis, Patricia K. Nguyen Human Coronary plaque T cells are clonal and cross-react to virus and self Circulation Research 2022 Apr 5

Immune changes beyond Th2 pathways during rapid multifood immunotherapy enabled with omalizumab.

Manohar M, Dunham D, Gupta S, Yan Z, Zhang W, Minnicozzi S, Kirkey M, Bunning B, Roy Chowdhury R, Galli SJ, Boyd SD, Kost LE, Chinthrajah RS, Desai M, Oettgen HC, Maecker HT, Yu W, DeKruyff RH, Andorf S, Nadeau KC. Immune changes beyond Th2 pathways during rapid multifood immunotherapy enabled with omalizumab. Allergy. 2021 Mar 30.

PMID: 33782956

Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion.

Huang H, Sikora MJ, Islam S, Roy Chowdhury R, Chien YH, Scriba TJ, Davis MM, Steinmetz LM. Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion. Proc Natl Acad Sci U S A. 2019 04 30; 116(18):8995-9001.
PMID: 30992377

A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes.

Roy Chowdhury R, Vallania F, Yang Q, Lopez Angel CJ, Darboe F, Penn-Nicholson A, Rozot V, Nemes E, Malherbe ST, Ronacher K, Walzl G, Hanekom W, Davis MM, Winter J, Chen X, Scriba TJ, Khatri P, Chien YH. A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes. Nature. 2018 08; 560(7720):644-648.
PMID: 30135583   

Lymphocytes: Gamma Delta

Chien YH, Roy Chowdhury R. Lymphocytes: Gamma Delta First published: 15 October 2015 https://doi.org/10.1002/9780470015902.a0001195.pub3

Efficacy of phytol-derived diterpenoid immunoadjuvants over alum in shaping the murine host’s immune response to Staphylococcus aureus.

Roy Chowdhury R, Fitch RW, Ghosh SK. Efficacy of phytol-derived diterpenoid immunoadjuvants over alum in shaping the murine host’s immune response to Staphylococcus aureus. Vaccine. 2013 Feb 06; 31(8):1178-86.
PMID: 23313815

Synthetic adjuvants for vaccine formulations: phytol derivatives.

Ghosh SK, Roy Chowdhury R. Synthetic adjuvants for vaccine formulations: phytol derivatives. Expert Opin Drug Deliv. 2013 Apr; 10(4):437-50.
PMID: 23293963

Effects of small intestinal submucosa (SIS) on the murine innate immune microenvironment induced by heat-killed Staphylococcus aureus.

Roy Chowdhury R, Aachoui Y, Ghosh SK. Effects of small intestinal submucosa (SIS) on the murine innate immune microenvironment induced by heat-killed Staphylococcus aureus. PLoS One. 2012; 7(11):e48724.
PMID: 23189134

Phytol-derived novel isoprenoid immunostimulants.

Roy Chowdhury R, Ghosh SK. Phytol-derived novel isoprenoid immunostimulants. Front Immunol. 2012; 3:49.
PMID: 22566931

Molecular signatures of phytol-derived immunostimulants in the context of chemokine-cytokine microenvironment and enhanced immune response.

Aachoui Y, Roy Chowdhury R, Fitch RW, Ghosh SK. Molecular signatures of phytol-derived immunostimulants in the context of chemokine-cytokine microenvironment and enhanced immune response. Cell Immunol. 2011; 271(2):227-38.
PMID: 21813116

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